I am an applied mathematician combining mathematical modelling and machine learning to understand the mechanisms underlying neurodegenerative diseases. I am currently based in the Klenerman Lab at the University of Cambridge, where I work closely with experimental colleagues. In 2025 I completed my DPhil at the Mathematical Institute, University of Oxford, supervised by Prof Alain Goriely and Prof Ramin Golestanian.
Some more information about a few projects is below (or on Google Scholar). Please email me (mwc38 [at] cam [dot] ac [dot] uk) to get in touch.
some projects
- Protein aggregation Many dementia-causing diseases are associated with toxic protein aggregates. I have been thinking about what causes a cell to transition to disease and how we can design therapies. This news article provides an overview and some mathematical details are here.
- Phase separation Proteins can interact to form spatial patterns or structures. In an article published in Physical Review Letters, we showed a new catalysis-driven mechanism for phase separation. The press release explains what it’s all about.
- Football modelling Do you expect there to be an odd or even number of goals in a football match? As part of the Graham Hoare Prize, we tried to answer this and similar questions. Read the article or watch us discuss it on YouTube.